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Structure of Hæmoglobin: A Three-Dimensional Fourier Synthesis at 5.5-Å. Resolution, Obtained by X-Ray Analysis

PERUTZ, M. F., ROSSMANN, M. G., CULLIS, ANN F., MUIRHEAD, HILARY, WILL, GEORG, NORTH, A. C. T.

Journal:

Nature

Année:

1960

Fichier:

PDF, 744 KB

1960

Structure of a ternary complex of an allosteric lactate dehydrogenase from Bacillus stearothermophilus at 2·5 Å resolution

Dale B. Wigley, Steven J. Gamblin, Johan P. Turkenburg, Eleanor J. Dodson, Klaus Piontek, Hilary Muirhead, J.John Holbrook

Journal:

Journal of Molecular Biology

Année:

1992

Langue:

english

Fichier:

PDF, 2.66 MB

english, 1992

The Enzymes of Glycolysis: Structure, Activity and Evolution || Glucose-6-Phosphate Isomerase

A. Achari, S. E. Marshall, Hilary Muirhead, R. H. Palmieri and E. A. Noltmann

Journal:

Philosophical Transactions of the Royal Society of London Series B Biological Sciences (1934-1990)

Année:

1981

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1981

A general method of domain closure is applied to phosphoglycerate kinase and the result compared with the crystal structure of a closed conformation of the enzyme

Nagasuma R. Chandra, Hilary Muirhead, J. John Holbrook, Bradley E. Bernstein, Wim G.J. Hol, Richard B. Sessions

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1998

Langue:

english

Fichier:

PDF, 424 KB

english, 1998

Eight novel mutations and consequences on mRNA and protein level in pyruvate kinase-deficient patients with nonspherocytic hemolytic anemia

Wilfried Kugler, Christian Willaschek, Christiane Holtz, Andreas Ohlenbusch, Petra Laspe, Regina Krügener, Hilary Muirhead, Werner Schröter, Max Lakomek

Journal:

Human Mutation

Année:

2000

Langue:

english

Fichier:

PDF, 409 KB

english, 2000

A prediction of the tertiary structure of human phospholipase A2 from synovial fluid and a model of substrate binding

Mark Kelly, Richard B. Sessions, Hilary Muirhead

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1992

Langue:

english

Fichier:

PDF, 498 KB

english, 1992

Crystal structure of phosphoglucose isomerase from pig muscle and its complex with 5-phosphoarabinonate

Christopher Davies, Hilary Muirhead

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2002

Langue:

english

Fichier:

PDF, 78 KB

english, 2002

Molecular basis of neurological dysfunction coupled with haemolytic anaemia in human glucose-6-phosphate isomerase (GPI) deficiency

Wilfried Kugler, Kathrin Breme, Petra Laspe, Hilary Muirhead, Christopher Davies, Heinz Winkler, Werner Schröter, M. Lakomek

Journal:

Human Genetics

Année:

1998

Langue:

english

Fichier:

PDF, 281 KB

english, 1998

Structure Of Hæemoglobin: A Three-Dimensional Fourier Synthesis of Reduced Human Haemoglobin at 5.5 Å Resolution

MUIRHEAD, HILARY, PERUTZ, M. F.

Journal:

Nature

Année:

1963

Fichier:

PDF, 1.25 MB

1963

Structure of Hæmoglobin : An X-ray Examination of Reduced Horse Hæmoglobin

PERUTZ, M. F., BOLTON, W., DIAMOND, R., MUIRHEAD, HILARY, WATSON, H. C.

Journal:

Nature

Année:

1964

Fichier:

PDF, 370 KB

1964

Identification of Residues responsible for the Alkaline Bohr Effect in Haemoglobin

PERUTZ, M. F., MUIRHEAD, HILARY, MAZZARELLA, L., CROWTHER, R. A., GREER, J., KILMARTIN , J. V.

Journal:

Nature

Année:

1969

Fichier:

PDF, 434 KB

1969

Three-dimensional Fourier Synthesis of Tosyl-elastase at 3.5 Å Resolution

WATSON, H. C., SHOTTON, D. M., COX, JOYCE M., MUIRHEAD, HILARY

Journal:

Nature

Année:

1970

Fichier:

PDF, 715 KB

1970

Three-dimensional Fourier Synthesis of Human Deoxyhaemoglobin at 3.5 Å Resolution

MUIRHEAD, HILARY, GREER, J.

Journal:

Nature

Année:

1970

Fichier:

PDF, 740 KB

1970

Structure of pyruvate kinase and similarities with other enzymes: possible implications for protein taxonomy and evolution

Levine, Michael, Muirhead, Hilary, Stammers, David K., Stuart, David I.

Journal:

Nature

Année:

1978

Fichier:

PDF, 494 KB

1978

The engineering of a more thermally stable lactate dehydrogenase by reduction of the area of a water-accessible hydrophobic surface

Dale B. Wigley, Anthony R. Clarke, Cameron R. Dunn, David A. Barstow, Tony Atkinson, William N. Chia, Hilary Muirhead, J.John Holbrook

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

1987

Langue:

english

Fichier:

PDF, 303 KB

english, 1987

Glycolytic enzymes: From hexose to pyruvate

Hilary Muirhead, Herman Watson

Journal:

Current Biology

Année:

1992

Langue:

english

Fichier:

PDF, 133 KB

english, 1992

A comparison of the structure and activity of cat and trout muscle pyruvate kinases

Richard N. HARKINS, Jennifer C. NOCTON, Margaret P. RUSSELL, Linda A. FOTHERGILL, Hilary MUIRHEAD

Journal:

FEBS Journal

Année:

1983

Langue:

english

Fichier:

PDF, 601 KB

english, 1983

Purification, characterisation and mutagenesis of highly expressed recombinant yeast pyruvate kinase

Toby H. L. MURCOTT, Teresa McNALLY, Simon C. ALLEN, Linda A. FOTHERGILL-GILMORE, Hilary MUIRHEAD

Journal:

FEBS Journal

Année:

1991

Langue:

english

Fichier:

PDF, 774 KB

english, 1991

Allosteric Activation in Bacillus stearothermophilus Lactate Dehydrogenase Investigated by an X-ray Crystallographic Analysis of a Mutant Designed to Prevent Tetramerization of the Enzyme

Alexander D. Cameron, David I. Roper, Kathleen M. Moreton, Hilary Muirhead, J.John Holbrook, Dale B. Wigley

Journal:

Journal of Molecular Biology

Année:

1994

Fichier:

PDF, 682 KB

1994

Cooperativity in Bacillus stearothermophilus pyruvate kinase

Simon C Lovell, Abdul H Mullick, Hilary Muirhead

Journal:

Journal of Molecular Biology

Année:

1998

Langue:

english

Fichier:

PDF, 321 KB

english, 1998

The crystal structure of human phosphoglucose isomerase at 1.6 Å resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia

Jon Read, Jake Pearce, Xiaochun Li, Hilary Muirhead, John Chirgwin, Christopher Davies

Journal:

Journal of Molecular Biology

Année:

2001

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2001

Pyruvate Kinase ofTrypanosoma brucei:Overexpression, Purification, and Functional Characterization of Wild-Type and Mutated Enzyme

Isabelle Ernest, Mia Callens, Antonio D. Uttaro, Nathalie Chevalier, Fred R. Opperdoes, Hilary Muirhead, Paul A.M. Michels

Journal:

Protein Expression and Purification

Année:

1998

Langue:

english

Fichier:

PDF, 114 KB

english, 1998

The active site of glucose phosphate isomerase

Peter J. Shaw, Hilary Muirhead

Journal:

FEBS Letters

Année:

1976

Langue:

english

Fichier:

PDF, 650 KB

english, 1976

Key residues in the allosteric transition of Bacillus stearothermophilus pyruvate kinase identified by site-directed mutagenesis

Dianne Walker, William N. Chia, Hilary Muirhead

Journal:

Journal of Molecular Biology

Année:

1992

Langue:

english

Fichier:

PDF, 1.65 MB

english, 1992

The Crystal Structure of Mouse Phosphoglucose Isomerase at 1.6 Å Resolution and its Complex with Glucose 6-Phosphate Reveals the Catalytic Mechanism of Sugar Ring Opening

J.T. Graham Solomons, Ella M. Zimmerly, Suzanne Burns, N. Krishnamurthy, Michael K. Swan, Sandra Krings, Hilary Muirhead, John Chirgwin, Christopher Davies

Journal:

Journal of Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 681 KB

english, 2004

Three-dimensional structure of pig muscle phosphoglucose isomerase at 6 Å resolution

Hilary Muirhead, Peter J. Shaw

Journal:

Journal of Molecular Biology

Année:

1974

Langue:

english

Fichier:

PDF, 637 KB

english, 1974

Three-dimensional structure of cat muscle pyruvate kinase at 6 Å resolution

David K. Stammers, Hilary Muirhead

Journal:

Journal of Molecular Biology

Année:

1975

Langue:

english

Fichier:

PDF, 6.55 MB

english, 1975

Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 Å

David I. Stuart, Michael Levine, Hilary Muirhead, David K. Stammers

Journal:

Journal of Molecular Biology

Année:

1979

Langue:

english

Fichier:

PDF, 10.77 MB

english, 1979

Crystallization of a ternary complex of lactate dehydrogenase from Bacillus stearothermophilus

Dale B. Wigley, Hilary Muirhead, Steven J. Gamblin, J.John Holbrook

Journal:

Journal of Molecular Biology

Année:

1988

Langue:

english

Fichier:

PDF, 261 KB

english, 1988

Crystallographic structure analysis of glucose 6-phosphate isomerase at 3·5 Å resolution

Peter J. Shaw, Hilary Muirhead

Journal:

Journal of Molecular Biology

Année:

1977

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1977

Three-dimensional structure of cat muscle pyruvate kinase at 3·1 Å resolution

David K. Stammers, Hilary Muirhead

Journal:

Journal of Molecular Biology

Année:

1977

Langue:

english

Fichier:

PDF, 593 KB

english, 1977

Glycolytic enzymes: from hexose to pyruvate

Muirhead, Hilary, Watson, Herman

Journal:

Current Opinion in Structural Biology

Année:

1992

Langue:

english

Fichier:

PDF, 645 KB

english, 1992

Personnel

Muirhead, Hilary, Watson, Herman

Journal:

Brain and Development

Année:

1989

Fichier:

PDF, 145 KB

1989

Triose phosphate isomerase, pyruvate kinase and other α/β-barrel enzymes

Muirhead, Hilary

Journal:

Trends in Biochemical Sciences

Année:

1983

Langue:

english

Fichier:

PDF, 541 KB

english, 1983

Structure and function of haemoglobin

Muirhead, Hilary, Cox, Joyce M., Mazzarella, L., Perutz, M.F.

Journal:

Journal of Molecular Biology

Année:

1967

Langue:

english

Fichier:

PDF, 8.83 MB

english, 1967

A comparison of adult and foetal horse haemoglobins

Perutz, M.F., Muirhead, Hilary, Glauser, Stanley C., Stockell, Anne

Journal:

Journal of Molecular Biology

Année:

1961

Langue:

english

Fichier:

PDF, 238 KB

english, 1961

Mechanisms of cooperativity and allosteric regulation in proteins

Muirhead, Hilary

Journal:

Trends in Biochemical Sciences

Année:

1990

Langue:

english

Fichier:

PDF, 126 KB

english, 1990

The Structure of Haemoglobin. VIII. A Three-Dimensional Fourier Synthesis at 5·5 Å Resolution: Determination of the Phase Angles

Ann F. Cullis, Hilary Muirhead, M. F. Perutz, M. G. Rossmann and A. C. T. North

Journal:

Proceedings of the Royal Society of London Series A Mathematical and Physical Sciences (1934-1990)

Année:

1961

Langue:

english

Fichier:

PDF, 2.60 MB

english, 1961

The Structure of Haemoglobin. IX. A Three-Dimensional Fourier Synthesis at 5·5 Å Resolution: Description of the Structure

Ann F. Cullis, Hilary Muirhead, M. F. Perutz, M. G. Rossmann and A. C. T. North

Journal:

Proceedings of the Royal Society of London Series A Mathematical and Physical Sciences (1934-1990)

Année:

1962

Langue:

english

Fichier:

PDF, 4.69 MB

english, 1962

Ligand-induced conformational changes in wild-type and mutant yeast pyruvate kinase

Collins, Richard A., Kelly, Sharon M., Price, Nicholas C., Fothergill-Gilmore, Linda A., Muirhead, Hilary

Journal:

Protein Engineering Design and Selection

Année:

1996

Langue:

english

Fichier:

PDF, 5.24 MB

english, 1996

Structure of Cat Muscle Pyruvate Kinase at 0.6 nm (6 Å) Resolution

MUIRHEAD, HILARY, STAMMERS, DAVID K.

Journal:

Biochemical Society Transactions

Année:

1974

Langue:

english

Fichier:

PDF, 242 KB

english, 1974

Structure of Cat Muscle Pyruvate Kinase at 0.26 nm Resolution

STAMMERS, DAVID K., LEVINE, MICHAEL, STUART, DAVID I., MUIRHEAD, HILARY

Journal:

Biochemical Society Transactions

Année:

1977

Langue:

english

Fichier:

PDF, 261 KB

english, 1977

Isoenzymes of pyruvate kinase

MUIRHEAD, HILARY

Journal:

Biochemical Society Transactions

Année:

1990

Langue:

english

Fichier:

PDF, 402 KB

english, 1990

[Fortschritte der Chemischen Forschung] Naturstoffe Volume 6/1 || The structure of haemoglobin

Muirhead, Hilary

Année:

1966

Langue:

english

Fichier:

PDF, 1.65 MB

english, 1966